Abstract

CUQUETTO, Douglas Colombi; MILL, José Geraldo  and  AMARAL, Fabian Tadeu do. Influência do uso de fluoxetina sobre o tempo de corrida em esteira ergométrica em ratos não treinados. Rev. Bras. Educ. Fís. Esporte [online]. 2012, vol.26, n.03, pp.375-381. ISSN 1981-4690.

Works of different authors have been shown that an increase in the concentration of serotonin (5-HT) in the brain during intense and long-term physical exercise, is directly associated with a harm in the function of the Central Nervous System (CNS), with corresponding development of the fatigue and consequence decrease of the performance. In the present work, 10 rats Wistar were submitted to runsessions until the exhaustion in treadmill. The experimental protocols were splited in 4 phases: Phase 1: evaluation of the range run-time of the animals until the physical exhaustion. Phase 2: evaluation of the range run-time of the animals until the physical exhaustion on treatment with fluoxetine. Phase 3: washout seven days. Phase 4 washout 14 days. The present study suggest that chronic administration of fluoxetine increase substantially the run-time until the physical exhaustion in rats submitted to exercises in treadmill.

Keywords : Fluoxetin; Nervous System; Exhaustion.

        · abstract in Portuguese | Spanish     · text in Portuguese     · Portuguese ( pdf )