Abstract

SILVA-BATISTA, Carla et al. Comparison of spinal inhibitions between parkisonian and helathy individuals. Rev. Bras. Educ. Fís. Esporte [online]. 2013, vol.27, n.02, pp.187-197. ISSN 1981-4690.

The purposes of the present study were to compare presynaptic inhibition (PI) and disynaptic reciprocal inhibition (DRI) levels between parkinsonians and healthy individuals and to verify the correlation of such inhibitions with muscle rigidity and clinical severity (assessed by the Unified Parkinson Disease Rating Scale). We evaluated 11 parkinsonians in stages 2 and 3 of the disease and 13 healthy individuals matched for age. The PI was signifi cant lower in parkinsonians (31.6%) than in healthy individuals (67.1%) (p = 0.02). The DRI did not differ between parkinsonians (26.9%) and healthy individuals (27.6%) (p = 0.91). Furthermore, no significant correlation was observed between PI with muscle rigidity and clinical severity (p > 0.05). Therefore, inhibitory mechanisms do not fully explain the cause of muscle rigidity and clinical severity of parkinsonians. Changes between the activation of agonist and antagonist muscles seem to be caused by abnormal supraspinal influence on spinal mechanisms

Keywords : H-Reflex; Spinal Cord; Presynaptic Inhibition; Dissinaptic Reciprocal Inhibition; Parkinson’s Disease.

        · abstract in Portuguese     · text in Portuguese     · Portuguese ( pdf )